Hyperkeratotic Skin


Hyperkeratotic skin conditions, such as psoriasis and keratosis pilaris, are associated with increased transepidermal water loss (TEWL).1,2 Hyperkeratotic skin benefit from topical formulations that hydrate to soften keratin and promote desquamation, while remaining gentle to skin and respecting the skin barrier. CeraVe combines ingredients like salicylic acid and 10% urea paired with ceramides and hyaluronic acid to smooth skin and help restore the protective skin barrier.


Keratosis Pilaris


The CeraVe SA Smoothing Cleanser and Cream regimen was test on 45 women ages 18-50 years with moderate tactile and visual roughness additional mild to moderate follicular erythema on the upper arms or outer thighs diagnosed as keratosis pilaris by a dermatologist. Subjects showed a 76% decrease in dryness, 39% reduction in visual roughness and a 20% decrease in follicular erythema after 8 weeks. A 3D optical measurement technology confirmed these significant reduction in skin roughness.
  1. Gruber R, Sugarman JL, Crumrine D, et al. Sebaceous gland, hair shaft, and epidermal barrier abnormalities in keratosis pilaris with and without filaggrin deficiency. Am J Pathol. 2015;185(4):1012-1021.
  2. Ye L, Lv C, Man G, Song S, Elias PM, Man MQ. Abnormal epidermal barrier recovery in uninvolved skin supports the notion of an epidermal pathogenesis of psoriasis. J Invest Dermatol. 2014;134(11):2843-2846.
  3. Cho, Yunhi et al. “An inverse relationship between ceramide synthesis and clinical severity in patients with psoriasis.” Journal of Korean medical science vol. 19,6 (2004): 859-63. 
  4. “About Psoriasis.” National Psoriasis Foundation, National Psoriasis Foundation, https://www.psoriasis.org/about-psoriasis/. 
  5. Ye L, Lv C, Man G, Song S, Elias PM, Man MQ. Abnormal epidermal barrier recovery in uninvolved skin supports the notion of an epidermal pathogenesis of psoriasis. J Invest Dermatol. 2014;134(11):2843-2846.
  6. “About World Psoriasis Day.” International Federation of Psoriasis Associations, International Federation of Psoriasis Associations, https://www.psoriasis.org/world-psoriasis-day/.
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