Integrative skincare trial of 1064-NM picosecond laser followed by Phloretin, Vitamin C and Ferulic Acid serum for treatment of hyperpigmentation in photodamaged facial in latin skin

V. Campos, MD, C. Alves, MD, L. Zagonel, MD, C. Rocha, MD, L. Lopes, MD, P. Correia, BSc, M. Feiges Stoliar, BSc, J. Euzébio Junior, BSc and P. Brieva, PhD

INTRODUCTION

Hyperpigmentation is a common concern for Latin skin. Few published studies address overall skin rejuvenation in this group using picosecond laser (PL) to target pigmentation and stimulate dermal remodeling. The combination of Phloretin, Vitamin C and Ferulic Acid (PCF) topically has been shown to be efficient for the treatment of aging and hyperpigmentation on intact skin. The laser associated with drug delivery is a promising method to promote better penetration of actives into the skin, reduce side effects and improve results. The aim of this trial was to evaluate the short and long-term clinical efficacy of the combination of an antioxidant serum containing PCF with PL treatment.