Clinical Evaluation of the Moisturizing, Reduce redness and Oil-control Effects of a Lotion Containing Azelaic Acid, Alpha-arbutin with Botanical Ingredients on Sensitive Oily to Combination Skin

Song Weimin, Fei Liu, Zhitao Liu

BACKGROUND

Sensitive oily to combination skin has exuberant oil secretion, open pores and tends to have blackheads or acne. The typical characteristics of that type of skin are oily “Tzone” (forehead, nose, and chin) combined symptoms such as redness, itching, flaking, burning, or stinging. Due to its complex etiology and pathogenesis, effective treatments of sensitive oily to combination skin are lacking.

INTRODUCTION

Sensitive skin exhibits a variety of clinical signs and symptoms, including edema, erythema, facial flush, pruritus, burning, pain, and stinging1. Azelaic acid has profound anti-inflammatory, anti-oxidative effects2. Arbutin could be beneficial in treatment of hyperpigmentation disorders3. Botanical Ingredients could inhibit cytokines, which are associated with erythema, edema, skin pain, and pruritus4. This study aimed to prospectively evaluate the moisturizing, reduce redness and oil-control effects of a lotion containing Azelaic acid, Alpha-arbutin with Botanical ingredients on sensitive oily to combination skin in Chinese patients.