A Selenium Disulfide-based shampoo is beneficial in the management of various hair and scalp conditions: results from a real-world study conducted in China in 759 subjects

D. Zong, D. Yang, S. Leclerc-Mercier

INTRODUCTION & OBJECTIVES

Different scalp and hair conditions such as seborrheic dermatitis (SD)/dandruff, hair loss including androgenetic alopecia (AGA), scalp folliculitis, as well as inflammatory skin conditions, such as scalp psoriasis, impact, due to clinical signs and symptoms, the individuals’ quality of life (QoL).^{1, 2}
1% Selenium disulfide (SeS2)-based shampoo, also containing, 0.9% Salicylic Acid, Vitamin E and Ceramide-R, is effective in the treatment of dandruff, a milder form of seborrheic dermatitis.³
SeS2 has antifungal properties against Malassezia spp. and also inhibits Staphylococcus epidermidis growth in vitro and restores the microbial scalp equilibrium after 28 days of use. Moreover, it modifies the global bacterial distribution in decreasing Staphylococci and increasing Cutibacterium loads.^{4, 5}
Past reports on the treatment of scalp SD/Dandruff have focused on Malassezia spp. and counts, while bacterial microbiota changes have only been poorly described.^{6, 7}