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The replenishment of skin lipids on dry and damaged skin is a desirable therapeutic target to restore the barrier and to improve skin moisturization. Sustained release technology is designed to increase and maintain skin hydration by delivering moisturizing ingredients over time, improving the effect of a moisturizer. In this randomized, single‐blind, controlled trial a facial lotion containing ceramides, niacinamide and hyaluronic acid in a multilamellar vesicular emulsion (MVE) was tested for its influence on hydration in both dry and barrier disrupted skin in comparison to reference lotion with a soothing complex.